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Integrated variants from 13,000 complete genomes available to public in Kaviar database

The Institute for Systems Biology (ISB) and the Inova Translational Medicine Institute (ITMI) announced today a new release of Kaviar, the most comprehensive collection of human genomic variants currently available to the public. (EurakAlert! The Global Source for Science News)

Pushing P4

Good policy has to be guided by good science and a systems-driven medicine that is predictive, preventive, personalized and participatory (P4). Marginal changes to evidence-based medicine (e.g., computerizing data collection) will themselves have only marginal effects on improving healthcare and reducing its costs. By Colin Hill, Leroy Hood, Sui Hang, Stuart Kauffman. (Scientific American Worldview)

Personalized medicine: Time for one-person trials

Precision medicine requires a different type of clinical trial that focuses on individual, not average, responses to therapy, says Nicholas J. Schork. (Nature)

"Surviving Terminal Cancer" premieres at Lincoln Center

This documentary presents compelling evidence from doctors, regulators, and other patients that raises concern over the validity and ethical grounding of oncology research, and the resulting limitations to clinical practice. Is it possible that as a society we could make dramatic progress against cancer if we reconsidered our strategy, as opposed to blindly following a system that has failed to deliver meaningful results for over four decades? (Surviving Terminal Cancer)

Colin Hill attends President Obama's Precision Medicine Summit

"Precision medicine transcends the one-size-fits-all approach to get the right treatment to each individual patient the first time, and is transforming medicine and population health management. The result is a smarter, more impactful, and more efficient healthcare system,” says Colin Hill, GNS CEO and co-founder, and Transforming Medicine director and co-founder. (GNS Healthcare)

The newest new thing: Obama's precision medicine initiative

“Delivering on precision medicine’s promise is the culmination of many previous technological and policy efforts”, noted Colin Hill, co-founder and CEO of GNS Healthcare, a company specializing in precision analytics. (Modern Healthcare)

Transforming Medicine: A Manifesto

Integrating “best practices” with “alternative” methods to determine which therapies benefit patients the most. (Scientific American Worldview)

Thinker of Untold Dreams: A Portrait of Stuart Kauffman

A documentary about Stuart Kauffman. Some have called him the smartest man in the world. MacArthur Genius and scientist Stuart Kauffman is on a mission to create a theory that will transform all of science. (Vimeo On Demand)

How To Escape the Cancer Attractor: Rationale and Limitations of Multi-Target Drugs

Sui Huang and Stuart A. Kauffman, 2013.

Complex Gene Regulatory Networks – from Structure to Biological Observables: Cell Fate Determination

Sui Huang and Stuart A. Kauffman, 2009.

Gene Expression Dynamics in the Macrophage Exhibit Criticality

Stuart A. Kauffman, Leroy E. Hood, Ilya Shmulevich, et al., 2008.

Can Big Data Save My Dad From Cancer?

As CEO and founder of GNS Healthcare, Colin Hill oversees a team of mathematicians, biologists, and data scientists as they crunch and decode healthcare data to unlock the mysteries of what treatment will work for specific patients. (Forbes)

Moving healthcare from the Mad Men era into the big data age

When we know which treatments are effective for which patients, there is a dual benefit: better health outcomes and reduced costs. (Forbes)

Any knowledge that might be useful: Leroy Hood

“My fundamental philosophy is that you owe it to society to transfer to them any knowledge you have that might be useful.” (Scientific American)